职称：研究员

职务：实验设备处副处长

系所：纳米化学与生物学研究所

办公室：校本部东区环化楼401A室

电话：021-66138025-202

E-mail：xydeng@shu.edu.cn

个人简介

北京大学本科、硕士，亚星221net博士，美国休斯顿Methodist医院研究所博士后。一直从事纳米材料的合成、修饰、生物医学应用及相关毒理学研究。在Nature Biotechnology，Carbon，Journal of Materials Chemistry, Langmuir和Toxicology Letters等SCI杂志上发表论文50余篇，获授权发明专利4项。论文他因次数超过1300次(Google Scholar)。作为项目负责人承担多项国家级和省部级项目任务。2009年获亚星221net优秀青年教师称号，2012年入选嘉定区青年领军人才，2012年获优秀博士后。

学术经历

1999-2003年 北京大学化学学院学士学位

2003-2006年 北京大学化学学院硕士学位

2008-2010年 亚星221net博士（在职）

2010-2012年 美国休斯顿Methodist医院研究所博士后

研究方向

纳米医学，纳米毒理学

代表成果

[1].Xu, R.; Zhang, G.; Mai, J.; Deng, X.; Segura-Ibarra, V.; Wu, S.; Shen, J.; Liu, H.; Hu, Z.; Chen, L., An injectable nanoparticle generator enhances delivery of cancer therapeutics. Nature Biotechnology 2016, 34, 414.

[2].Zhang, K.; Deng, X.; Fu, Q.; Meng, Y.; Zhao, H.; Wang, W.; Wu, M.; Lei, Y., Photolithography Compatible Templated Patterning of Functional Organic Materials in Emulsion. Advanced Science 2015, DOI: 10.1002/advs.201500304.

[3].Wang, J.; Yang, X.; Chen, P.; Zhang, M.; Li, C.; Hang, M.; Deng, X.; Wu, M., Synthesis of short mesoporous silica nanotubes and their application in drug delivery. Nanomedicine: Nanotechnology, Biology, and Medicine 2016, 2 (12), 559.

[4].Song, Z. M.; Chen, N.; Liu, J. H.; Tang, H.; Deng, X.; Xi, W. S.; Han, K.; Cao, A.; Liu, Y.; Wang, H., Biological effect of food additive titanium dioxide nanoparticles on intestine: an in vitro study. Journal of Applied Toxicology 2015, 35 (10), 1169.

[5].Liu, Y.; Song, Z.-M.; Deng, X.; Cui, Y.; Yang, Y.-F.; Han, K.; Jin, R.; Wang, H.; Liu, Y.; Cao, A., Chitosan-coated red fluorescent protein nanoparticle as a potential dual-functional siRNA carrier. Nanomedicine-UK 2015, 10 (13), 2005.

[6].Wang, Y.; Zhu, L.; Yang, X.; Shao, E.; Deng, X.; Liu, N.; Wu, M., Facile synthesis of three-dimensional Mn3O4 hierarchical microstructures and their application in the degradation of methylene blue. Journal of Materials Chemistry A 2015, 3 (6), 2934-2941;

[7].Yan, Y.; Shao, E.; Deng, X.; Liu, J.; Zhang, Y.; Tang, Y., Microwave-assisted synthesis of Gd(iii)-loaded nanozeolite SOD as MRI contrast agent with remarkable stability in vivo. Journal of Materials Chemistry B 2014, 2 (20), 3041;

[8].Deng, X. Y.; Luo, M.; Shao, E. L.; Zhao, H.; Yang, X.; Ni, Q. S.; Jiao, Z. Long-term biodistribution, metabolism and toxicity of carbon nanotubes in vivo. Toxicology Letters 2013, 221, S242.

[9].Deng, X.; Qin, P.; Luo, M.; Shao, E.; Zhao, H.; Yang, X.; Wang, Y.; Shen, H.; Jiao, Z.; Wu, M. Mesoporous Silica Coating on Carbon Nanotubes: Layer-by-Layer Method. Langmuir 2013, 29 (23), 6815.

[10].Deng, X. Y.; Xiong, D. M.; Wang, Y. L.; Chen, W. T.; Luan, Q. X.; Zhang, H. J.; Jiao, Z.; Wu, M. H. Water soluble multi-Walled carbon nanotubes enhance peritoneal macrophage activity in vivo. Journal of Nanoscience and Nanotechnology 2010, 10, 8663.

[11].Ji, Z. F.; Zhang, D. Y.; Li, L.; Shen, X. Z.; Deng, X. Y.; Dong, L.; Wu, M. H.; Liu, Y. F. Hepatotoxicity of multi-walled carbon nanotubes in mice. Nanotechnology 2009, 20, 445101.

[12].Deng, X. Y.; Xiong, D.; Wang, H. F.; Chen, D. D.; Jiao, Z.; Zhang, H. J.; Wu, M. H. Bulk enrichment and separation of multi-walled carbon nanotubes by density gradient centrifugation. Carbon 2009, 47, 1608.

[13].Deng, X. Y.; Wu, F.; Liu, Z.; Luo, M.; Li, L.; Ni, Q. S.; Jiao, Z.; Wu, M. H.; Liu, Y. F. The splenic toxicity of water soluble multi-walled carbon nanotubes in mice. Carbon 2009, 47, 1421.

[14].Deng, X. Y.; Luan, Q. X.; Chen, W. T.; Wang, Y. L.; Wu, M. H.; Zhang, H. J.; Jiao, Z. Nanosized zinc oxide particles induce neural stem cell apoptosis. Nanotechnology 2009, 20, 115101.

[15].Deng, X. Y.; Yang, S. T.; Nie, H. Y.; Wang, H. F.; Liu, Y. F. A generally adoptable radiotracing method for tracking carbon nanotubes in animals. Nanotechnology 2008, 19, 075101.

[16].Deng, X.; Jia, G.; Wang, H.; Sun, H.; Wang, X.; Yang, S.; Wang, T.; Liu, Y. Translocation and fate of multi-walled carbon nanotubes in vivo. Carbon 2007, 45, 1419.

科研项目

国家自然科学基金

上海市自然科学基金

教授课程

环境毒理学（专业硕士）